Local Anesthetics Impair In Vitro Growth of Human Osteoblasts: A Laboratory Investigation

Introduction: Intraarticular infusion of Local Anesthetics (LAs) is widely used, but the direct effect of LAs on osteoblasts has not been extensively investigated. Therefore, we analyzed the effect of LAs on growing osteoblasts in an in vitro model. Methods: Growing fetal human osteoblasts were either exposed 2 or 9 days to lidocaine, bupivacaine or ropivacaine solutions at concentrations of 1.25, 0.62 and 0.3125...

Laryngeal Mask Airway (LMA) in Lacrimal Duct Surgery in Children is Safe?

In very young children General Anesthesia (GA) with Endotracheal Intubation (EI) is highly recommended even for short-term procedures including syringing and probing for congenital obstruction of the lacrimal duct. It is a simple and short term intervention but it is necessary to properly overcome some clinical problems occurring in clinical practice, due to GA with EI, such as risk of mucosal trauma, need of musc...

The Ultrasound-Guided Bilateral Erector Spinae Plane Block is an Effective and Safe Postoperative Analgesia Method at Liver Transplantation Recipient: 3 Cases Report

Introduction: In the context of the concept of rapid rehabilitation, the postoperative pain treatment of patients undergoing liver transplantation is facing challenges. Traditional methods of simple intravenous analgesia and epidural analgesia both have shortcomings and are difficult to adapt to clinical needs. With the clinical application of ultrasonography, peripheral nerve block has been widely carried out, su...

Perioperative Concerns of SARS-CoV-2 Vaccination and Anaesthesia

A 23 year old male presented with diagnosis of a vascular necrosis of hip and was posted for total hip replacement surgery. During pre-anaesthetic check up it was revealed that 2 days back he was vaccinated with first dose of Covishield vaccine. Following vaccine he developed fever at night for which he took paracetamol 650 mg. After paracetamol ingestion he developed rashes, which resolved spontaneously. Next day...

Tetral ogy of Fallot with Total Anomalous Pulmonary Venous Connection

A 15-month-old baby presented with increasing cyanosis and clubbing. His chest Xray showed ‘coeur en sabot’ and ‘figure-of-eight’ appearance. The diagnosis of tetralogy of Fallot with total anomalous pulmonary venous connection, an extremely rare combination, was confirmed with echocardiography and computed tomography scan. The significance of correct diagnosis; and potential merits and demerits of various cardiac...

Anesthetic Management of a Patient with Muscular Disease Using Remifentanil Plus Propofol without Neuromuscular Blockade

We have experienced three cases of an anesthetic management of a patient with muscular disease without neuromuscular blockade during induction of general anesthesia, including a 72-year-old woman with a 14-year history of multiple system atrophy who underwent arthroplasty of the temporomandibular joint, a 12-year-old woman with spinal muscular atrophy who underwent dental treatment, and a 20-yearold man with Charc...

Posterior Reversible Encephalopathy Syndrome (PRES): Case Report in a Woman with Pregnancy-Induced Hypertension

Posterior reversible encephalopathy syndrome is a clinical-radiological syndrome characterized by headache, visual disturbances, seizures, altered mental status and white matter vasogenic edema affecting the posterior occipital and parietal lobes of the brain predominantly. Its pathogenesis is not fully understood and two opposite theories have been proposed, both based on the central role of hypertension. Here we...

Anesthetic Experience of A Patient with Palpable Paratracheal Air Cysts in the Anterior Neck – A Case Report

Paratracheal Air Cysts (PACs) are clinical entities characterized by an out pouching of the trachea that can be encountered incidentally in the operating room. Most PACs are asymptomatic, but complications, such as difficult ventilation after intubation, difficulty in lung isolation, and tracheal rupture related to PACs, have been reported. Here, we report a case of a 63-year-old female whose large PACs were palpa...

Anesthesia in Ocular Surgery

Anaesthesia is required during ophthalmic surgeries so that surgical procedure can be performed without causing any discomfort to the patient. Type of anaesthesia depends upon type and duration of surgery, patient cooperation and surgeon’s preference. Over the years, a wide range of anesthetic techniques have been developed and have undergone modifications so as to provide better anesthesia with ease and minimum c...

Using Fully Immersive ‘In Situ’ Simulation to Prepare New Foundation Doctors to Work in an Acute Setting

Introduction: Patient safety around the time of medical changeover day is of interest worldwide. Negative perceptions have now been supported by evidence that patients who are admitted on the first Wednesday in August in England with a medical primary diagnosis have a higher early death rate. Junior doctors are often the first to assess deteriorating patients. Delay in admission to intensive care due to suboptimal...

The Clinical and Experimental Study on Jian Pi Yi Shen and Tong Du Xing Nao Acupuncture for Children with Cerebral Palsy

Clinical Study In this study, 146 cases of brain injury and 1078 cases of cerebral palsy were included by randomized controlled study with ICF (GMFM, Peabody fine motor function, Gesell, muscle tension, joint activity, ADL, TCD, skull B ultrasound, head CT / MRI, SPECT, DTI) evaluation method. The results showed that. The recovery rate of extracellular space (92.3%) was significantly higher than that of the contro...

Patient Doctor Communication in the Era of Medical Tourism

Medical tourism is a growing sector in India. The primary reason that attracts medical value travel to India is cost effectiveness and treatment from accredited facilities at par with developed countries at much lower cost. Usually the patients travel with interpreter or one is provided by the hospital for effective communication between the patient and doctor. The presence of an interpreter is invaluable in the p...

Validated Dutch Translation of the Clinical Frailty Scale for ICU Patients and its use in Practice

1.1. Introduction: To translate the Clinical Frailty Scale (CFS) into Dutch and subsequently explore the impact of an Intensive Care Unit (ICU) admission on frailty using the translated CFS and the extent of recovery following ICU discharge. 1.2. Methods: Translation of the CFS was performed according to the principles of good translation. Regarding the translation of item ‘vulnerable’ a survey among ICU nurses, i...